As a result of the work of the Stomadent Research Department (in cooperation with Nanolaboratory Nantes), the invention "Method of inducing apoptosis in neoplastic cells" was patented.

The present invention relates to a method of inducing apoptosis in neoplastic cells, particularly in the colon and lymphoblastic leukemia. The essence of the invention is a method of inducing apoptosis in neoplastic cells, which consists in treating neoplastic cells with saline after treatment in a plasma reactor. Low pressure and low temperature plasma saline was used to induce apoptosis in colorectal cancer cells and lymphoblastic leukemia.

Physicochemical studies have clearly shown that saline exposed to low-pressure and low-temperature plasma significantly changed its properties compared to its non-plasma counterpart in terms of pH, ectrolytic conductivity and surface tension.

Apoptosis, or programmed cell death, plays an important role in keeping the body functioning properly. Its lack or disruption of its functioning may have serious consequences, leading to the process of cancer formation. Neoplastic cells are those that do not undergo apoptosis. Currently used chemotherapy is mainly based on cytotoxic drugs that cause serious side effects.

Induction of apoptosis with saline, compared to the use of drugs or antibodies, is characterized by a relatively simpler procedure with less financial outlays and no adverse effects of therapy. The proposed use of plasma saline could be of key importance in medicine to limit the growth of tumors and other disease processes in which apoptosis plays a key role. The use of this method can reduce the cost of treatment and reduce side effects.